When do most adverse reactions to contrast generally occur?

Most adverse reactions to contrast agents typically occur within minutes of injection, with a significant proportion arising around 20 minutes post-injection, especially in cases of severe reactions. This time frame is critical because immediate monitoring after administration allows healthcare professionals to quickly recognize and respond to any adverse events.

The onset of reactions is often most pronounced in this initial period as the patient's body starts processing the contrast material, and immune responses may be triggered. Severe reactions, such as anaphylaxis or respiratory distress, can manifest swiftly and require prompt intervention. Recognizing this timing helps technologists and medical staff to ensure patient safety and preparedness during and immediately after contrast administration.